BDBM50098011 CHEMBL422557::N-Isopropyl-N-(1-methyl-1H-pyrazol-4-ylmethyl)-2-(2-phenyl-1H-indol-3-yl)-acetamide

SMILES: CC(C)N(Cc1cnn(C)c1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1

InChI Key: InChIKey=CSSSHHXWEPZWGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50098011 (CHEMBL422557 | N-Isopropyl-N-(1-methyl-1H-pyrazol-...) Show SMILES CC(C)N(Cc1cnn(C)c1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H26N4O/c1-17(2)28(16-18-14-25-27(3)15-18)23(29)13-21-20-11-7-8-12-22(20)26-24(21)19-9-5-4-6-10-19/h4-12,14-15,17,26H,13,16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	527	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for the inhibitory activity against human Farnesyltransferase				Bioorg Med Chem Lett 11: 865-9 (2001) BindingDB Entry DOI: 10.7270/Q2F47PPX
					More data for this Ligand-Target Pair