BindingDB PrimarySearch

BDBM50098560 CHEBI:63004::SODIUM BROMIDE::Sodium Bromide

SMILES: [Na+].[Br-]

InChI Key: InChIKey=JHJLBTNAGRQEKS-UHFFFAOYSA-M

Data: 14 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50098560
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	4.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse (IBBR)-CNR Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 4389-96 (2014) Article DOI: 10.1016/j.bmcl.2014.08.015 BindingDB Entry DOI: 10.7270/Q28054D1
					More data for this Ligand-Target Pair
Carbonic anhydrase (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	4.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere and Tampere University Hospital Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 4472-6 (2013) Article DOI: 10.1016/j.bmc.2013.05.058 BindingDB Entry DOI: 10.7270/Q28S4SV8
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 4402-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.014 BindingDB Entry DOI: 10.7270/Q2348N4M
Universit£ degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNR Curated by ChEMBL					Assay Description Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 4800-4804 (2017) Article DOI: 10.1016/j.bmc.2017.07.033 BindingDB Entry DOI: 10.7270/Q2028V0P
CNR Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tampere and Tampere University Hospital Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 4472-6 (2013) Article DOI: 10.1016/j.bmc.2013.05.058 BindingDB Entry DOI: 10.7270/Q28S4SV8
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method				Bioorg Med Chem 25: 575-580 (2017) Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay				Bioorg Med Chem Lett 24: 1127-32 (2014) Article DOI: 10.1016/j.bmcl.2013.12.124 BindingDB Entry DOI: 10.7270/Q2FX7DDZ
Kochi Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse, CNR Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...				Bioorg Med Chem 25: 2010-2015 (2017) BindingDB Entry DOI: 10.7270/Q2JD5012
Istituto di Bioscienze e Biorisorse, CNR Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse (IBBR)-CNR Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 4389-96 (2014) Article DOI: 10.1016/j.bmcl.2014.08.015 BindingDB Entry DOI: 10.7270/Q28054D1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse Curated by ChEMBL					Assay Description Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assay				Bioorg Med Chem 23: 4405-9 (2015) Article DOI: 10.1016/j.bmc.2015.06.021 BindingDB Entry DOI: 10.7270/Q2JD4ZJ0
Istituto di Bioscienze e Biorisorse Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC sid UniChem Similars	PubMed	6.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow method				Bioorg Med Chem 23: 4831-8 (2015) BindingDB Entry DOI: 10.7270/Q20V8FK8
University of Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC sid UniChem Similars	PubMed	>1.00E+8	n/a	n/a	n/a	n/a	n/a	n/a	8.3	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow method				Bioorg Med Chem 23: 4831-8 (2015) BindingDB Entry DOI: 10.7270/Q20V8FK8
University of Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-carbonic anhydrase (Methanosarcina thermophila)	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	1.60E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse Curated by ChEMBL					Assay Description Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay				Bioorg Med Chem 23: 4405-9 (2015) Article DOI: 10.1016/j.bmc.2015.06.021 BindingDB Entry DOI: 10.7270/Q2JD4ZJ0
Istituto di Bioscienze e Biorisorse Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-carbonic anhydrase (Methanosarcina thermophila)	BDBM50098560 (CHEBI:63004 \| SODIUM BROMIDE \| Sodium Bromide) Show SMILES [Na+].[Br-] Show InChI InChI=1S/BrH.Na/h1H;/q;+1/p-1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC sid UniChem Similars	Article PubMed	1.60E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...				Bioorg Med Chem 25: 575-580 (2017) Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair