BDBM50098586 Benzofuran-2-carboxylic acid (3-methyl-1-{1-methyl-3-[methyl-(pyridine-2-sulfonyl)-amino]-2-oxo-propylcarbamoyl}-butyl)-amide::CHEMBL416579

SMILES: CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@@H](C)C(=O)CN(C)S(=O)(=O)c1ccccn1

InChI Key: InChIKey=QQZLBKZIHBAHHH-HKUYNNGSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50098586 (Benzofuran-2-carboxylic acid (3-methyl-1-{1-methyl...) Show SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@@H](C)C(=O)CN(C)S(=O)(=O)c1ccccn1 Show InChI InChI=1S/C25H30N4O6S/c1-16(2)13-19(28-25(32)22-14-18-9-5-6-10-21(18)35-22)24(31)27-17(3)20(30)15-29(4)36(33,34)23-11-7-8-12-26-23/h5-12,14,16-17,19H,13,15H2,1-4H3,(H,27,31)(H,28,32)/t17-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Human cathepsin K				J Med Chem 44: 1380-95 (2001) BindingDB Entry DOI: 10.7270/Q2QR4WDC
					More data for this Ligand-Target Pair				3D Structure (docked)