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BDBM50098718 CHEMBL3593330

SMILES: CC(C)(C)c1cc(no1)C(=O)C(=N\Nc1ccc(Cl)c(Cl)c1)\C#N

InChI Key: InChIKey=XTKWJEPUEPTGJL-FYJGNVAPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098718   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 4


(Mus musculus)		BDBM50098718
PNG
(CHEMBL3593330)
Show SMILES CC(C)(C)c1cc(no1)C(=O)C(=N\Nc1ccc(Cl)c(Cl)c1)\C#N
Show InChI InChI=1S/C16H14Cl2N4O2/c1-16(2,3)14-7-12(22-24-14)15(23)13(8-19)21-20-9-4-5-10(17)11(18)6-9/h4-7,20H,1-3H3/b21-13+
PDB

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UniProtKB/TrEMBL

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UniChem

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Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay

J Med Chem 58: 6033-47 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00635
BindingDB Entry DOI: 10.7270/Q29025JD
More data for this
Ligand-Target Pair