BDBM50098800 CHEMBL3593872

SMILES: COc1cc(C(=O)c2ccc3n(C)ccc3c2)c(O)c(OC)c1OC

InChI Key: InChIKey=GESIDFQWZILMBW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin alpha chain /beta chain (Bos taurus)	BDBM50098800 (CHEMBL3593872) Show SMILES COc1cc(C(=O)c2ccc3n(C)ccc3c2)c(O)c(OC)c1OC Show InChI InChI=1S/C19H19NO5/c1-20-8-7-11-9-12(5-6-14(11)20)16(21)13-10-15(23-2)18(24-3)19(25-4)17(13)22/h5-10,22H,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization after 30 mins				Bioorg Med Chem 23: 4230-6 (2015) Article DOI: 10.1016/j.bmc.2015.06.043 BindingDB Entry DOI: 10.7270/Q2571DS7
					More data for this Ligand-Target Pair