BDBM50098814 CHEMBL277194::N-{2-Methyl-1-[5-(1-methyl-cyclopropyl)-[1,3,4]oxadiazole-2-carbonyl]-propyl}-2-(6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetamide

SMILES: CC(C)[C@H](NC(=O)Cn1c(nccc1=O)-c1ccccc1)C(=O)c1nnc(o1)C1(C)CC1

InChI Key: InChIKey=SCIVRVWOMXUIGH-SFHVURJKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50098814 (CHEMBL277194 | N-{2-Methyl-1-[5-(1-methyl-cyclopro...) Show SMILES CC(C)[C@H](NC(=O)Cn1c(nccc1=O)-c1ccccc1)C(=O)c1nnc(o1)C1(C)CC1 Show InChI InChI=1S/C23H25N5O4/c1-14(2)18(19(31)21-26-27-22(32-21)23(3)10-11-23)25-16(29)13-28-17(30)9-12-24-20(28)15-7-5-4-6-8-15/h4-9,12,14,18H,10-11,13H2,1-3H3,(H,25,29)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	26.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cortech, Inc. Curated by ChEMBL					Assay Description Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrate				J Med Chem 44: 1268-85 (2001) BindingDB Entry DOI: 10.7270/Q2B858VW
					More data for this Ligand-Target Pair