BDBM50099036 CHEMBL11009::{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]-ethyl}-(4-pyridin-4-yl-butyl)-amine

SMILES: Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccncc1

InChI Key: InChIKey=DTLBVHBEDJEATA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50099036 (CHEMBL11009 | {2-[2-(3,5-Dimethyl-phenyl)-1H-indol...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccncc1 Show InChI InChI=1S/C27H31N3/c1-20-17-21(2)19-23(18-20)27-25(24-8-3-4-9-26(24)30-27)12-16-28-13-6-5-7-22-10-14-29-15-11-22/h3-4,8-11,14-15,17-19,28,30H,5-7,12-13,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50099036 (CHEMBL11009 | {2-[2-(3,5-Dimethyl-phenyl)-1H-indol...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccncc1 Show InChI InChI=1S/C27H31N3/c1-20-17-21(2)19-23(18-20)27-25(24-8-3-4-9-26(24)30-27)12-16-28-13-6-5-7-22-10-14-29-15-11-22/h3-4,8-11,14-15,17-19,28,30H,5-7,12-13,16H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 11: 1077-80 (2001) BindingDB Entry DOI: 10.7270/Q2J102FK
					More data for this Ligand-Target Pair