BDBM50099172 1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-urea::CHEMBL368176

SMILES: Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1

InChI Key: InChIKey=JZBDUKNRWKGIPH-HSZRJFAPSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50099172 (1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...) Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of human sst3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM50099172 (1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...) Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of human sst1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50099172 (1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...) Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of human sst5 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50099172 (1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...) Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of human sst4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50099172 (1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...) Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibition of human sst2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN
					More data for this Ligand-Target Pair