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SMILES: F[C@@H]1CCNCC1c1c[nH]c2cc(F)ccc12

InChI Key: InChIKey=HGYQATXPDPUIQH-PIJUOVFKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099256   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50099256
PNG
(6-Fluoro-3-(4-fluoro-piperidin-3-yl)-1H-indole | C...)
Show SMILES F[C@@H]1CCNCC1c1c[nH]c2cc(F)ccc12
Show InChI InChI=1S/C13H14F2N2/c14-8-1-2-9-10(7-17-13(9)5-8)11-6-16-4-3-12(11)15/h1-2,5,7,11-12,16-17H,3-4,6H2/t11?,12-/m1/s1
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 70n/an/an/an/an/an/an/an/a



Merck Sharp and Dohme

Curated by ChEMBL


Assay Description
Ability to displace [3H]-ketanserin binding to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cells

J Med Chem 44: 1603-14 (2001)


BindingDB Entry DOI: 10.7270/Q27M076K
More data for this
Ligand-Target Pair