BDBM50099408 CHEMBL3356955

SMILES: NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C#Cc1ccccc1

InChI Key: InChIKey=WFNZZJNAYSLGAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50099408 (CHEMBL3356955) Show SMILES NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(cc1)C#Cc1ccccc1 Show InChI InChI=1S/C21H16N2O5S2/c22-29(25,26)19-8-4-5-9-20(19)30(27,28)23-21(24)18-14-12-17(13-15-18)11-10-16-6-2-1-3-7-16/h1-9,12-15H,(H,23,24)(H2,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Pharmaceuticals Limited Curated by ChEMBL					Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells using PGH2 as substrate incubated for 10 mins prior to substrate addition measured aft...				Bioorg Med Chem Lett 24: 4838-44 (2014) Article DOI: 10.1016/j.bmcl.2014.08.056 BindingDB Entry DOI: 10.7270/Q2X068MN
					More data for this Ligand-Target Pair