BDBM50099674 CHEMBL47836::[1-(4-Chloro-benzoyl)-5-(2-hydroxy-ethoxy)-2-methyl-1H-indol-3-yl]-acetic acid

SMILES: Cc1c(CC(O)=O)c2cc(OCCO)ccc2n1C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=ULSXNQVHBXBRTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50099674 (CHEMBL47836 | [1-(4-Chloro-benzoyl)-5-(2-hydroxy-e...) Show SMILES Cc1c(CC(O)=O)c2cc(OCCO)ccc2n1C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18ClNO5/c1-12-16(11-19(24)25)17-10-15(27-9-8-23)6-7-18(17)22(12)20(26)13-2-4-14(21)5-3-13/h2-7,10,23H,8-9,11H2,1H3,(H,24,25)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Aldose reductase (AR)				J Med Chem 44: 1718-28 (2001) BindingDB Entry DOI: 10.7270/Q2N0177X
					More data for this Ligand-Target Pair