BDBM50099804 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-pyrrolidin-2-ylmethyl)-amide::CHEMBL54662

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1C2CCCC1CCC2

InChI Key: InChIKey=OXPSOFUXALIQFQ-MCLLYFMISA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50099804 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1C2CCCC1CCC2 |TLB:21:22:29.28.30:25.24.26| Show InChI InChI=1S/C26H33BrN2O2/c1-31-25-21-13-3-2-12-20(21)23(27)15-22(25)26(30)28-16-19-11-6-14-29(19)24-17-7-4-8-18(24)10-5-9-17/h2-3,12-13,15,17-19,24H,4-11,14,16H2,1H3,(H,28,30)/t17?,18?,19-,24?/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]-IABN the radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50099804 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1C2CCCC1CCC2 |TLB:21:22:29.28.30:25.24.26| Show InChI InChI=1S/C26H33BrN2O2/c1-31-25-21-13-3-2-12-20(21)23(27)15-22(25)26(30)28-16-19-11-6-14-29(19)24-17-7-4-8-18(24)10-5-9-17/h2-3,12-13,15,17-19,24H,4-11,14,16H2,1H3,(H,28,30)/t17?,18?,19-,24?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma-1 receptor measured on guinea pig brain membranes using [3H]-(+)-pentazocine as radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50099804 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1C2CCCC1CCC2 |TLB:21:22:29.28.30:25.24.26| Show InChI InChI=1S/C26H33BrN2O2/c1-31-25-21-13-3-2-12-20(21)23(27)15-22(25)26(30)28-16-19-11-6-14-29(19)24-17-7-4-8-18(24)10-5-9-17/h2-3,12-13,15,17-19,24H,4-11,14,16H2,1H3,(H,28,30)/t17?,18?,19-,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 long expressed in Sf9 cells using [125I]-IABN radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair