BDBM50099995 4-((1-(3-phenoxybenzyl)-1H-imidazol-5-yl)methyl)-1-(4-(trifluoromethyl)phenyl)piperazin-2-one::4-[3-(3-Phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-1-(4-trifluoromethyl-phenyl)-piperazin-2-one::CHEMBL31610

SMILES: FC(F)(F)c1ccc(cc1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O

InChI Key: InChIKey=HBYRYAHMXSFRDA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50099995 (4-((1-(3-phenoxybenzyl)-1H-imidazol-5-yl)methyl)-1...) Show SMILES FC(F)(F)c1ccc(cc1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O Show InChI InChI=1S/C28H25F3N4O2/c29-28(30,31)22-9-11-23(12-10-22)35-14-13-33(19-27(35)36)18-24-16-32-20-34(24)17-21-5-4-8-26(15-21)37-25-6-2-1-3-7-25/h1-12,15-16,20H,13-14,17-19H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition against human Geranylgeranyl transferase type I catalyzed by incorporation of [3H]- GGPP (geranylgeranyl pyrophosphate) into biot...				Bioorg Med Chem Lett 11: 1411-5 (2001) BindingDB Entry DOI: 10.7270/Q2MP52J0
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50099995 (4-((1-(3-phenoxybenzyl)-1H-imidazol-5-yl)methyl)-1...) Show SMILES FC(F)(F)c1ccc(cc1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O Show InChI InChI=1S/C28H25F3N4O2/c29-28(30,31)22-9-11-23(12-10-22)35-14-13-33(19-27(35)36)18-24-16-32-20-34(24)17-21-5-4-8-26(15-21)37-25-6-2-1-3-7-25/h1-12,15-16,20H,13-14,17-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition against human Farnesyltransferase catalyzed by incorporation of [3H]- FPP into recombinant Ras-CVIM				Bioorg Med Chem Lett 11: 1411-5 (2001) BindingDB Entry DOI: 10.7270/Q2MP52J0
					More data for this Ligand-Target Pair