BDBM50100291 2-(3-Cyano-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL23011

SMILES: N#Cc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key: InChIKey=ABWZCEYXTRZCFY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50100291 (2-(3-Cyano-phenoxy)-4-imidazol-1-ylmethyl-benzonit...) Show SMILES N#Cc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1 Show InChI InChI=1S/C18H12N4O/c19-10-14-2-1-3-17(8-14)23-18-9-15(4-5-16(18)11-20)12-22-7-6-21-13-22/h1-9,13H,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50100291 (2-(3-Cyano-phenoxy)-4-imidazol-1-ylmethyl-benzonit...) Show SMILES N#Cc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1 Show InChI InChI=1S/C18H12N4O/c19-10-14-2-1-3-17(8-14)23-18-9-15(4-5-16(18)11-20)12-22-7-6-21-13-22/h1-9,13H,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair