BDBM50100455 3-[(E)-4-(4-Dimethylamino-benzoyl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-acrylamide::3-[4-(4-Dimethylamino-benzoyl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-acrylamide::CHEMBL51060

SMILES: CN(C)c1ccc(cc1)C(=O)c1cc(\C=C\C(=O)NO)n(C)c1

InChI Key: InChIKey=YYJNJTYRTHFTKU-CMDGGOBGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50100455 (3-[(E)-4-(4-Dimethylamino-benzoyl)-1-methyl-1H-pyr...) Show SMILES CN(C)c1ccc(cc1)C(=O)c1cc(\C=C\C(=O)NO)n(C)c1 Show InChI InChI=1S/C17H19N3O3/c1-19(2)14-6-4-12(5-7-14)17(22)13-10-15(20(3)11-13)8-9-16(21)18-23/h4-11,23H,1-3H3,(H,18,21)/b9-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase activity				J Med Chem 44: 2069-72 (2001) BindingDB Entry DOI: 10.7270/Q2959GT3
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50100455 (3-[(E)-4-(4-Dimethylamino-benzoyl)-1-methyl-1H-pyr...) Show SMILES CN(C)c1ccc(cc1)C(=O)c1cc(\C=C\C(=O)NO)n(C)c1 Show InChI InChI=1S/C17H19N3O3/c1-19(2)14-6-4-12(5-7-14)17(22)13-10-15(20(3)11-13)8-9-16(21)18-23/h4-11,23H,1-3H3,(H,18,21)/b9-8+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description In vitro for anti-HD2 (Histone deacetylase 2) activity in maize				J Med Chem 45: 1778-84 (2002) BindingDB Entry DOI: 10.7270/Q2C53K55
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50100455 (3-[(E)-4-(4-Dimethylamino-benzoyl)-1-methyl-1H-pyr...) Show SMILES CN(C)c1ccc(cc1)C(=O)c1cc(\C=C\C(=O)NO)n(C)c1 Show InChI InChI=1S/C17H19N3O3/c1-19(2)14-6-4-12(5-7-14)17(22)13-10-15(20(3)11-13)8-9-16(21)18-23/h4-11,23H,1-3H3,(H,18,21)/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description In vitro for anti-HDAC1 (Histone deacetylase 1) activity in mouse A20 cells				J Med Chem 45: 1778-84 (2002) BindingDB Entry DOI: 10.7270/Q2C53K55
					More data for this Ligand-Target Pair