BindingDB PrimarySearch

BDBM50100871 (Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one::(Z)-1-Benzooxazol-2-yl-octadec-9-en-1-one::1-Benzooxazol-2-yl-nonadec-10-en-2-one::CHEMBL285678

SMILES: CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1

InChI Key: InChIKey=APIPEDDJLOMNRC-KTKRTIGZSA-N

Data: 7 KI 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50100871
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against fatty acid amide hydrolase (FAAH)				Bioorg Med Chem Lett 11: 1517-20 (2001) BindingDB Entry DOI: 10.7270/Q2NG4PWS
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as conversion [14]C-oleamide to oleic acid				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille Curated by ChEMBL					Assay Description Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysis				J Med Chem 60: 4-46 (2017) Article DOI: 10.1021/acs.jmedchem.6b00538 BindingDB Entry DOI: 10.7270/Q2348NZC
Universit£ de Lille Curated by ChEMBL					More data for this Ligand-Target Pair
Anandamide amidohydrolase (Mus musculus (mouse))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitor affinity of the compound towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or ...				Bioorg Med Chem Lett 15: 1423-8 (2005) Article DOI: 10.1016/j.bmcl.2004.12.085 BindingDB Entry DOI: 10.7270/Q2PK0FNK
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Triacylglycerol hydrolase				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligand				Bioorg Med Chem Lett 15: 1423-8 (2005) Article DOI: 10.1016/j.bmcl.2004.12.085 BindingDB Entry DOI: 10.7270/Q2PK0FNK
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligand				Bioorg Med Chem Lett 15: 1423-8 (2005) Article DOI: 10.1016/j.bmcl.2004.12.085 BindingDB Entry DOI: 10.7270/Q2PK0FNK
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50100871 ((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one \| (Z...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against Fatty-acid amide hydrolase				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair