BDBM50101178 2-(3,5-Dimethyl-phenyl)-3-{2-[4-(4-methanesulfonylamino-phenyl)-butylamino]-ethyl}-1H-indole-5-carboxylic acid diisobutylamide::CHEMBL297151

SMILES: CC(C)CN(CC(C)C)C(=O)c1ccc2[nH]c(c(CCNCCCCc3ccc(NS(C)(=O)=O)cc3)c2c1)-c1cc(C)cc(C)c1

InChI Key: InChIKey=ICFPDSWFZNRQEB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101178 (2-(3,5-Dimethyl-phenyl)-3-{2-[4-(4-methanesulfonyl...) Show SMILES CC(C)CN(CC(C)C)C(=O)c1ccc2[nH]c(c(CCNCCCCc3ccc(NS(C)(=O)=O)cc3)c2c1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C38H52N4O3S/c1-26(2)24-42(25-27(3)4)38(43)31-13-16-36-35(23-31)34(37(40-36)32-21-28(5)20-29(6)22-32)17-19-39-18-9-8-10-30-11-14-33(15-12-30)41-46(7,44)45/h11-16,20-23,26-27,39-41H,8-10,17-19,24-25H2,1-7H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cells				Bioorg Med Chem Lett 11: 1723-6 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MK4
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101178 (2-(3,5-Dimethyl-phenyl)-3-{2-[4-(4-methanesulfonyl...) Show SMILES CC(C)CN(CC(C)C)C(=O)c1ccc2[nH]c(c(CCNCCCCc3ccc(NS(C)(=O)=O)cc3)c2c1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C38H52N4O3S/c1-26(2)24-42(25-27(3)4)38(43)31-13-16-36-35(23-31)34(37(40-36)32-21-28(5)20-29(6)22-32)17-19-39-18-9-8-10-30-11-14-33(15-12-30)41-46(7,44)45/h11-16,20-23,26-27,39-41H,8-10,17-19,24-25H2,1-7H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition GnRH-stimulated luteinizing hormone (LH) release from rat pituitary cells				Bioorg Med Chem Lett 11: 1723-6 (2001) BindingDB Entry DOI: 10.7270/Q2KH0MK4
					More data for this Ligand-Target Pair