BDBM50101669 (RS)2-{4-[2-[1-(4-Methoxy-benzyl)-4-methyl-2-oxo-2,3-dihydro-pyridin-3-ylcarbamoyl]-2-(2-naphthalen-2-yl-acetylamino)-ethyl]-phenyl}-2-methyl-propionic acid::CHEMBL79648

SMILES: COc1ccc(Cn2ccc(C)c(NC(=O)C(Cc3ccc(cc3)C(C)(C)C(O)=O)NC(=O)Cc3ccc4ccccc4c3)c2=O)cc1

InChI Key: InChIKey=LBXUJEDKVBNQHM-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50101669 ((RS)2-{4-[2-[1-(4-Methoxy-benzyl)-4-methyl-2-oxo-2...) Show SMILES COc1ccc(Cn2ccc(C)c(NC(=O)C(Cc3ccc(cc3)C(C)(C)C(O)=O)NC(=O)Cc3ccc4ccccc4c3)c2=O)cc1 Show InChI InChI=1S/C39H39N3O6/c1-25-19-20-42(24-27-12-17-32(48-4)18-13-27)37(45)35(25)41-36(44)33(22-26-10-15-31(16-11-26)39(2,3)38(46)47)40-34(43)23-28-9-14-29-7-5-6-8-30(29)21-28/h5-21,33H,22-24H2,1-4H3,(H,40,43)(H,41,44)(H,46,47)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd. Curated by ChEMBL					Assay Description Binding affinity for p56lck SH2 domain site				J Med Chem 44: 2421-31 (2001) BindingDB Entry DOI: 10.7270/Q26T0NB3
					More data for this Ligand-Target Pair