BDBM50101685 CHEMBL3394913

SMILES: COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)ccc1OCCN1CCCC1

InChI Key: InChIKey=FIDCSAAIHNKBJM-ZTKZIYFRSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101685 (CHEMBL3394913) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)ccc1OCCN1CCCC1 Show InChI InChI=1S/C28H30N4O4/c1-35-26-19-21(9-14-25(26)36-18-17-32-15-5-6-16-32)20-29-31-28(34)23-10-12-24(13-11-23)30-27(33)22-7-3-2-4-8-22/h2-4,7-14,19-20H,5-6,15-18H2,1H3,(H,30,33)(H,31,34)/b29-20+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair