BDBM50101742 CHEMBL3394895

SMILES: CCCCC(=O)Nc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(OC)c1

InChI Key: InChIKey=JDYIARKCILFUMT-WSDLNYQXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101742 (CHEMBL3394895) Show SMILES CCCCC(=O)Nc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(OC)c1 Show InChI InChI=1S/C20H22BrN3O4/c1-3-4-5-18(25)23-15-8-6-14(7-9-15)20(27)24-22-12-13-10-16(21)19(26)17(11-13)28-2/h6-12,26H,3-5H2,1-2H3,(H,23,25)(H,24,27)/b22-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair