BDBM50102321 11-[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl]-dibenzo[b,f][1,4]thiazepine::CHEMBL126658

SMILES: C(C1CCCO1)N1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12

InChI Key: InChIKey=BWMIMNUXQCHAAF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50102321 (11-[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl...) Show SMILES C(C1CCCO1)N1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 |t:14| Show InChI InChI=1S/C22H25N3OS/c1-3-9-20-18(7-1)22(23-19-8-2-4-10-21(19)27-20)25-13-11-24(12-14-25)16-17-6-5-15-26-17/h1-4,7-10,17H,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals LP Curated by ChEMBL					Assay Description Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.				J Med Chem 44: 372-89 (2001) BindingDB Entry DOI: 10.7270/Q2639P1N
					More data for this Ligand-Target Pair