BDBM50102326 11-[4-(3,4-Dimethoxy-butyl)-piperazin-1-yl]-dibenzo[b,f][1,4]thiazepine::CHEMBL129277

SMILES: COCC(CCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12)OC

InChI Key: InChIKey=BJVUMFJTYVBRMZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50102326 (11-[4-(3,4-Dimethoxy-butyl)-piperazin-1-yl]-dibenz...) Show SMILES COCC(CCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12)OC |t:13| Show InChI InChI=1S/C23H29N3O2S/c1-27-17-18(28-2)11-12-25-13-15-26(16-14-25)23-19-7-3-5-9-21(19)29-22-10-6-4-8-20(22)24-23/h3-10,18H,11-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals LP Curated by ChEMBL					Assay Description Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.				J Med Chem 44: 372-89 (2001) BindingDB Entry DOI: 10.7270/Q2639P1N
					More data for this Ligand-Target Pair