BDBM50102354 3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylpropan-1-one::3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-phenyl-propan-1-one::CHEMBL134676

SMILES: COc1ccccc1N1CCN(CCC(=O)c2ccccc2)CC1

InChI Key: InChIKey=HSQVZFKXMAGWDA-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50102354 (3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...) Show SMILES COc1ccccc1N1CCN(CCC(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O2/c1-24-20-10-6-5-9-18(20)22-15-13-21(14-16-22)12-11-19(23)17-7-3-2-4-8-17/h2-10H,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligand				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102354 (3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...) Show SMILES COc1ccccc1N1CCN(CCC(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O2/c1-24-20-10-6-5-9-18(20)22-15-13-21(14-16-22)12-11-19(23)17-7-3-2-4-8-17/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Para£ba Curated by ChEMBL					Assay Description Antagonist activity at 5HT1A				Eur J Med Chem 45: 1508-14 (2010) Article DOI: 10.1016/j.ejmech.2009.12.059 BindingDB Entry DOI: 10.7270/Q2HX1DX1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102354 (3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...) Show SMILES COc1ccccc1N1CCN(CCC(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O2/c1-24-20-10-6-5-9-18(20)22-15-13-21(14-16-22)12-11-19(23)17-7-3-2-4-8-17/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				Eur J Med Chem 43: 364-72 (2008) Article DOI: 10.1016/j.ejmech.2007.03.036 BindingDB Entry DOI: 10.7270/Q2SQ91NB
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50102354 (3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...) Show SMILES COc1ccccc1N1CCN(CCC(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O2/c1-24-20-10-6-5-9-18(20)22-15-13-21(14-16-22)12-11-19(23)17-7-3-2-4-8-17/h2-10H,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetine				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair