BDBM50102786 2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-carboxamidine::CHEMBL91962

SMILES: NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O

InChI Key: InChIKey=SJOGQFLRNCUNDK-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against Human Serine Protease Urokinase Plasminogen Activator				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inihibtion of Human Serine Protease tissue type Plasminogen Activator				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Human Serine Protease Plasmin				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity against Human Serine Protease Trypsin				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50102786 (2-(5-Bromo-2-hydroxy-biphenyl-3-yl)-1H-indole-5-ca...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(Br)cc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16BrN3O/c22-15-10-16(12-4-2-1-3-5-12)20(26)17(11-15)19-9-14-8-13(21(23)24)6-7-18(14)25-19/h1-11,25-26H,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity against Human Serine Protease Thrombin				J Med Chem 44: 2753-71 (2001) BindingDB Entry DOI: 10.7270/Q2RX9BC7
					More data for this Ligand-Target Pair