BDBM50103164 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL68271

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO

InChI Key: InChIKey=MQDWBVIPJPRWIJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50103164 (2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-15-24(21-8-4-3-5-9-21)26(25(16-19)27(31)29-32)30(18-20-7-6-14-28-17-20)36(33,34)23-12-10-22(35-2)11-13-23/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103164 (2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-15-24(21-8-4-3-5-9-21)26(25(16-19)27(31)29-32)30(18-20-7-6-14-28-17-20)36(33,34)23-12-10-22(35-2)11-13-23/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103164 (2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-15-24(21-8-4-3-5-9-21)26(25(16-19)27(31)29-32)30(18-20-7-6-14-28-17-20)36(33,34)23-12-10-22(35-2)11-13-23/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50103164 (2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H25N3O5S/c1-19-15-24(21-8-4-3-5-9-21)26(25(16-19)27(31)29-32)30(18-20-7-6-14-28-17-20)36(33,34)23-12-10-22(35-2)11-13-23/h3-17,32H,18H2,1-2H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair