BDBM50103171 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-3'-trifluoromethyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL304730

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=RMZUAMXVNUZHBB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50103171 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C28H24F3N3O5S/c1-18-13-21(20-6-3-7-22(14-20)28(29,30)31)15-25(27(35)33-36)26(18)34(17-19-5-4-12-32-16-19)40(37,38)24-10-8-23(39-2)9-11-24/h3-16,36H,17H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	542	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotease-1				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50103171 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C28H24F3N3O5S/c1-18-13-21(20-6-3-7-22(14-20)28(29,30)31)15-25(27(35)33-36)26(18)34(17-19-5-4-12-32-16-19)40(37,38)24-10-8-23(39-2)9-11-24/h3-16,36H,17H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro inhibition of TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50103171 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C28H24F3N3O5S/c1-18-13-21(20-6-3-7-22(14-20)28(29,30)31)15-25(27(35)33-36)26(18)34(17-19-5-4-12-32-16-19)40(37,38)24-10-8-23(39-2)9-11-24/h3-16,36H,17H2,1-2H3,(H,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50103171 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C28H24F3N3O5S/c1-18-13-21(20-6-3-7-22(14-20)28(29,30)31)15-25(27(35)33-36)26(18)34(17-19-5-4-12-32-16-19)40(37,38)24-10-8-23(39-2)9-11-24/h3-16,36H,17H2,1-2H3,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description In vitro ability to inhibit matrix metalloprotease-9.				Bioorg Med Chem Lett 11: 2189-92 (2001) BindingDB Entry DOI: 10.7270/Q2154HK0
					More data for this Ligand-Target Pair