BindingDB logo
myBDB logout

BDBM50103277 1-[3-Benzoyl-4-(2-naphthalen-2-yl-acetylamino)-phenylcarbamoyl]-2-mercapto-ethyl-ammonium; chloride::CHEMBL99997

SMILES: [NH3+][C@@H](CS)C(=O)Nc1ccc(NC(=O)Cc2ccc3ccccc3c2)c(c1)C(=O)c1ccccc1

InChI Key: InChIKey=JSRBFPUGRGUQAI-DEOSSOPVSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103277   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Saccharomyces cerevisiae (Baker's yeast))		BDBM50103277
PNG
(1-[3-Benzoyl-4-(2-naphthalen-2-yl-acetylamino)-phe...)
Show SMILES [NH3+][C@@H](CS)C(=O)Nc1ccc(NC(=O)Cc2ccc3ccccc3c2)c(c1)C(=O)c1ccccc1
Show InChI InChI=1S/C28H25N3O3S/c29-24(17-35)28(34)30-22-12-13-25(23(16-22)27(33)20-7-2-1-3-8-20)31-26(32)15-18-10-11-19-6-4-5-9-21(19)14-18/h1-14,16,24,35H,15,17,29H2,(H,30,34)(H,31,32)/p+1/t24-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 460n/an/an/an/an/an/a



Philipps-Universität Marburg

Curated by ChEMBL


Assay Description
Inhibitory activity against farnesyltransferase.

J Med Chem 44: 2886-99 (2001)


BindingDB Entry DOI: 10.7270/Q2TQ60TB
More data for this
Ligand-Target Pair