BDBM50103281 1-(3-Benzoyl-4-diphenylacetylamino-phenylcarbamoyl)-2-mercapto-ethyl-ammonium; chloride::CHEMBL431632

SMILES: [NH3+][C@@H](CS)C(=O)Nc1ccc(NC(=O)C(c2ccccc2)c2ccccc2)c(c1)C(=O)c1ccccc1

InChI Key: InChIKey=PTLJRRAZNROODO-VWLOTQADSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Saccharomyces cerevisiae (Baker's yeast))	BDBM50103281 (1-(3-Benzoyl-4-diphenylacetylamino-phenylcarbamoyl...) Show SMILES [NH3+][C@@H](CS)C(=O)Nc1ccc(NC(=O)C(c2ccccc2)c2ccccc2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C30H27N3O3S/c31-25(19-37)29(35)32-23-16-17-26(24(18-23)28(34)22-14-8-3-9-15-22)33-30(36)27(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-18,25,27,37H,19,31H2,(H,32,35)(H,33,36)/p+1/t25-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-Universität Marburg Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase.				J Med Chem 44: 2886-99 (2001) BindingDB Entry DOI: 10.7270/Q2TQ60TB
					More data for this Ligand-Target Pair