BDBM50103624 40602::CEPHALORIDINE::CHEBI:3537::Cefaloridine::Cephaloridine::Kefloridin::Loridine
SMILES: [H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)Cc1cccs1)C([O-])=O
InChI Key: InChIKey=CZTQZXZIADLWOZ-CRAIPNDOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Solute carrier family 22 member 8 (Rattus norvegicus) | BDBM50103624 (40602 | CEPHALORIDINE | CHEBI:3537 | Cefaloridine ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1.14E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells | Life Sci 70: 1861-74 (2002) Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 6 (Rattus norvegicus) | BDBM50103624 (40602 | CEPHALORIDINE | CHEBI:3537 | Cefaloridine ...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1.32E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells | Life Sci 70: 1861-74 (2002) Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Homo sapiens) | BDBM50103624 (40602 | CEPHALORIDINE | CHEBI:3537 | Cefaloridine ...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Georgia Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM) in OCTN2-expressing HeLa cells | J Biol Chem 275: 1699-707 (2000) Article DOI: 10.1074/jbc.275.3.1699 BindingDB Entry DOI: 10.7270/Q2CF9SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pregnane X receptor (Homo sapiens (Human)) | BDBM50103624 (40602 | CEPHALORIDINE | CHEBI:3537 | Cefaloridine ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
National Institutes of Health Chemical Genomics Center Curated by ChEMBL | Assay Description Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assay | Drug Metab Dispos 39: 151-9 (2010) Article DOI: 10.1124/dmd.110.035105 BindingDB Entry DOI: 10.7270/Q2JS9S5P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 6 (Homo sapiens (Human)) | BDBM50103624 (40602 | CEPHALORIDINE | CHEBI:3537 | Cefaloridine ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cells | Anal Biochem 283: 49-55 (2000) Article DOI: 10.1006/abio.2000.4633 BindingDB Entry DOI: 10.7270/Q2DR2ZC6 | |||||||||||
More data for this Ligand-Target Pair |