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SMILES: Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)-c1ccc(CNS(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=WSBHZSVKKICZAF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103703   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50103703
PNG
(CHEMBL308508 | N-{4-[5-Amino-1-(4-trifluoromethyl-...)
Show SMILES Nc1cc(nn1-c1ccc(cc1)C(F)(F)F)-c1ccc(CNS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C23H19F3N4O2S/c24-23(25,26)18-10-12-19(13-11-18)30-22(27)14-21(29-30)17-8-6-16(7-9-17)15-28-33(31,32)20-4-2-1-3-5-20/h1-14,28H,15,27H2
KEGG

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 114n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards human neuropeptide Y receptor type 5 in HEK 293 cell line, using [125I]-PYY as radioligand

Bioorg Med Chem Lett 11: 2283-6 (2001)


BindingDB Entry DOI: 10.7270/Q2NZ86WB
More data for this
Ligand-Target Pair