BDBM50103841 8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-4H-benzo[1,4]oxazin-3-one::CHEMBL305920
SMILES: O=C1COc2c(N1)cccc2N1CCN(Cc2cccc(c2)-c2ccccc2)CC1
InChI Key: InChIKey=FMEYZGBIOSKJJC-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50103841 (8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-4H-benzo[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description Binding affinity for dopamine receptor D2 determined using [3H]-spiperone | Bioorg Med Chem Lett 11: 2345-9 (2001) BindingDB Entry DOI: 10.7270/Q2RR1XH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50103841 (8-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-4H-benzo[...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]-8-OH-DPAT as radioligand | Bioorg Med Chem Lett 11: 2345-9 (2001) BindingDB Entry DOI: 10.7270/Q2RR1XH9 | |||||||||||
More data for this Ligand-Target Pair |