BDBM50103875 8-Allyl-7-(1,1-dimethyl-allyloxy)-chromen-2-one::CHEMBL311013

SMILES: CC(C)(Oc1ccc2ccc(=O)oc2c1CC=C)C=C

InChI Key: InChIKey=NRWXKUNIMMFBEZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 5-alpha-reductase (Homo sapiens (Human))	BDBM50103875 (8-Allyl-7-(1,1-dimethyl-allyloxy)-chromen-2-one | ...) Show SMILES CC(C)(Oc1ccc2ccc(=O)oc2c1CC=C)C=C Show InChI InChI=1S/C17H18O3/c1-5-7-13-14(20-17(3,4)6-2)10-8-12-9-11-15(18)19-16(12)13/h5-6,8-11H,1-2,7H2,3-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)				Bioorg Med Chem Lett 11: 2361-3 (2001) BindingDB Entry DOI: 10.7270/Q2RR1ZS9
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50103875 (8-Allyl-7-(1,1-dimethyl-allyloxy)-chromen-2-one | ...) Show SMILES CC(C)(Oc1ccc2ccc(=O)oc2c1CC=C)C=C Show InChI InChI=1S/C17H18O3/c1-5-7-13-14(20-17(3,4)6-2)10-8-12-9-11-15(18)19-16(12)13/h5-6,8-11H,1-2,7H2,3-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)				Bioorg Med Chem Lett 11: 2361-3 (2001) BindingDB Entry DOI: 10.7270/Q2RR1ZS9
					More data for this Ligand-Target Pair