BDBM50103905 CHEMBL3594099

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5cccc(c5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=XZVXDGZDMCMMGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103905 (CHEMBL3594099) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5cccc(c5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C38H39F4N5O5/c1-23-12-16-46(17-13-23)15-6-18-51-34-22-30-28(21-33(34)50-4)31(11-14-43-30)52-32-10-9-26(20-29(32)39)44-36(48)35-24(2)47(37(49)45(35)3)27-8-5-7-25(19-27)38(40,41)42/h5,7-11,14,19-23H,6,12-13,15-18H2,1-4H3,(H,44,48)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair