BDBM50103914 CHEMBL3593884

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(F)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1

InChI Key: InChIKey=RWEHIWZVWCPBHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103914 (CHEMBL3593884) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(F)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C35H34F3N5O6/c1-21-33(41(2)35(45)43(21)23-6-7-25(36)26(37)18-23)34(44)40-22-5-8-30(27(38)17-22)49-29-9-10-39-28-20-32(31(46-3)19-24(28)29)48-14-4-11-42-12-15-47-16-13-42/h5-10,17-20H,4,11-16H2,1-3H3,(H,40,44)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair