BDBM50103918 CHEMBL3593691

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Cl)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=SGSBKUVYAFXXPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103918 (CHEMBL3593691) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Cl)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H39ClFN5O5/c1-23-13-17-43(18-14-23)16-5-19-48-34-22-30-28(21-33(34)47-4)31(12-15-40-30)49-32-11-8-26(20-29(32)39)41-36(45)35-24(2)44(37(46)42(35)3)27-9-6-25(38)7-10-27/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,41,45)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair