BDBM50103921 CHEMBL3593688

SMILES: COc1ccc(cc1)-n1c(C)c(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCN(C)CC5)c(OC)cc34)c(F)c2)n(C)c1=O

InChI Key: InChIKey=JQLIANVZZPMVDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103921 (CHEMBL3593688) Show SMILES COc1ccc(cc1)-n1c(C)c(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCN(C)CC5)c(OC)cc34)c(F)c2)n(C)c1=O Show InChI InChI=1S/C37H41FN6O6/c1-24-35(42(3)37(46)44(24)26-8-10-27(47-4)11-9-26)36(45)40-25-7-12-32(29(38)21-25)50-31-13-14-39-30-23-34(33(48-5)22-28(30)31)49-20-6-15-43-18-16-41(2)17-19-43/h7-14,21-23H,6,15-20H2,1-5H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair