BDBM50103923 CHEMBL3593684

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key: InChIKey=DIKIYXVXEHVPSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103923 (CHEMBL3593684) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H39FN6O5/c1-24-34(41(3)36(45)43(24)26-9-6-5-7-10-26)35(44)39-25-11-12-31(28(37)21-25)48-30-13-14-38-29-23-33(32(46-4)22-27(29)30)47-20-8-15-42-18-16-40(2)17-19-42/h5-7,9-14,21-23H,8,15-20H2,1-4H3,(H,39,44)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair