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BDBM50104416 (S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3-bora-tricyclo[6.1.1.0*1,5*]dec-3-yl)-butyric acid::CHEMBL315413

SMILES: CC1(C)C2C[C@@]11OB(CC[C@H](NC(=O)OCc3ccccc3)C(O)=O)O[C@@]1(C)CC2

InChI Key: InChIKey=DZXMLXAQVHHBKX-WXMUEFQHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104416   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)		BDBM50104416
PNG
((S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](NC(=O)OCc3ccccc3)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C22H30BNO6/c1-20(2)16-9-11-21(3)22(20,13-16)30-23(29-21)12-10-17(18(25)26)24-19(27)28-14-15-7-5-4-6-8-15/h4-8,16-17H,9-14H2,1-3H3,(H,24,27)(H,25,26)/t16?,17-,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)

Bioorg Med Chem Lett 11: 2561-4 (2001)


BindingDB Entry DOI: 10.7270/Q29K49H7
More data for this
Ligand-Target Pair