BDBM50104598 2-Benzyloxycarbonylamino-3-{[(R)-1-(3-piperidin-4-yl-propionyl)-piperidine-3-carbonyl]-amino}-propionic acid::CHEMBL421547::RWJ-53419
SMILES: OC(=O)[C@H](CNC(=O)[C@@H]1CCCN(C1)C(=O)CCC1CCNCC1)NC(=O)OCc1ccccc1
InChI Key: InChIKey=MUWWGBUXCFRNCO-RTWAWAEBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50104598 (2-Benzyloxycarbonylamino-3-{[(R)-1-(3-piperidin-4-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of thrombin-induced human gel-filtered platelet aggregation | Bioorg Med Chem Lett 11: 2619-22 (2001) BindingDB Entry DOI: 10.7270/Q2DB8141 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50104598 (2-Benzyloxycarbonylamino-3-{[(R)-1-(3-piperidin-4-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIa | Bioorg Med Chem Lett 11: 2619-22 (2001) BindingDB Entry DOI: 10.7270/Q2DB8141 | |||||||||||
More data for this Ligand-Target Pair |