BDBM50104966 CHEMBL420487::N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-(2-hydroxy-indan-1-yl)-succinamide

SMILES: ONC(=O)C[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key: InChIKey=QDCHOZJXLIIHRT-BJZITVGISA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50104966 (CHEMBL420487 | N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C20H22N2O5/c23-15-7-5-12(6-8-15)9-14(11-18(25)22-27)20(26)21-19-16-4-2-1-3-13(16)10-17(19)24/h1-8,14,17,19,23-24,27H,9-11H2,(H,21,26)(H,22,25)/t14-,17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-8				J Med Chem 44: 3347-50 (2001) BindingDB Entry DOI: 10.7270/Q2057F7H
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50104966 (CHEMBL420487 | N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C20H22N2O5/c23-15-7-5-12(6-8-15)9-14(11-18(25)22-27)20(26)21-19-16-4-2-1-3-13(16)10-17(19)24/h1-8,14,17,19,23-24,27H,9-11H2,(H,21,26)(H,22,25)/t14-,17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of human matrix metalloprotease-9				J Med Chem 44: 3347-50 (2001) BindingDB Entry DOI: 10.7270/Q2057F7H
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50104966 (CHEMBL420487 | N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C20H22N2O5/c23-15-7-5-12(6-8-15)9-14(11-18(25)22-27)20(26)21-19-16-4-2-1-3-13(16)10-17(19)24/h1-8,14,17,19,23-24,27H,9-11H2,(H,21,26)(H,22,25)/t14-,17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	408	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-2				J Med Chem 44: 3347-50 (2001) BindingDB Entry DOI: 10.7270/Q2057F7H
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50104966 (CHEMBL420487 | N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N...) Show SMILES ONC(=O)C[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 Show InChI InChI=1S/C20H22N2O5/c23-15-7-5-12(6-8-15)9-14(11-18(25)22-27)20(26)21-19-16-4-2-1-3-13(16)10-17(19)24/h1-8,14,17,19,23-24,27H,9-11H2,(H,21,26)(H,22,25)/t14-,17-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	946	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-1				J Med Chem 44: 3347-50 (2001) BindingDB Entry DOI: 10.7270/Q2057F7H
					More data for this Ligand-Target Pair