null

SMILES: COc1ccc(CN2CCN(CC2)C(=O)CCn2cc(C)c3ccccc23)cc1OCc1ccccc1

InChI Key: InChIKey=RXWYCJKVGBGHNC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Homo sapiens (Human))	BDBM50105112 (1-[4-(3-Benzyloxy-4-methoxy-benzyl)-piperazin-1-yl...) Show SMILES COc1ccc(CN2CCN(CC2)C(=O)CCn2cc(C)c3ccccc23)cc1OCc1ccccc1 Show InChI InChI=1S/C31H35N3O3/c1-24-21-34(28-11-7-6-10-27(24)28)15-14-31(35)33-18-16-32(17-19-33)22-26-12-13-29(36-2)30(20-26)37-23-25-8-4-3-5-9-25/h3-13,20-21H,14-19,22-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against L-type calcium channel verapamil site				J Med Chem 44: 3391-401 (2001) BindingDB Entry DOI: 10.7270/Q2057GN9
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50105112 (1-[4-(3-Benzyloxy-4-methoxy-benzyl)-piperazin-1-yl...) Show SMILES COc1ccc(CN2CCN(CC2)C(=O)CCn2cc(C)c3ccccc23)cc1OCc1ccccc1 Show InChI InChI=1S/C31H35N3O3/c1-24-21-34(28-11-7-6-10-27(24)28)15-14-31(35)33-18-16-32(17-19-33)22-26-12-13-29(36-2)30(20-26)37-23-25-8-4-3-5-9-25/h3-13,20-21H,14-19,22-23H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligand				J Med Chem 44: 3391-401 (2001) BindingDB Entry DOI: 10.7270/Q2057GN9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50105112 (1-[4-(3-Benzyloxy-4-methoxy-benzyl)-piperazin-1-yl...) Show SMILES COc1ccc(CN2CCN(CC2)C(=O)CCn2cc(C)c3ccccc23)cc1OCc1ccccc1 Show InChI InChI=1S/C31H35N3O3/c1-24-21-34(28-11-7-6-10-27(24)28)15-14-31(35)33-18-16-32(17-19-33)22-26-12-13-29(36-2)30(20-26)37-23-25-8-4-3-5-9-25/h3-13,20-21H,14-19,22-23H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Binding affinity against mu opiate receptor				J Med Chem 44: 3391-401 (2001) BindingDB Entry DOI: 10.7270/Q2057GN9
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50105112 (1-[4-(3-Benzyloxy-4-methoxy-benzyl)-piperazin-1-yl...) Show SMILES COc1ccc(CN2CCN(CC2)C(=O)CCn2cc(C)c3ccccc23)cc1OCc1ccccc1 Show InChI InChI=1S/C31H35N3O3/c1-24-21-34(28-11-7-6-10-27(24)28)15-14-31(35)33-18-16-32(17-19-33)22-26-12-13-29(36-2)30(20-26)37-23-25-8-4-3-5-9-25/h3-13,20-21H,14-19,22-23H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
F-59000 Lille Curated by ChEMBL					Assay Description Inhibition of human adenosine A3 receptor				J Med Chem 44: 3391-401 (2001) BindingDB Entry DOI: 10.7270/Q2057GN9
					More data for this Ligand-Target Pair