BDBM50105257 CHEMBL3597683

SMILES: Fc1ccc(Cl)c(F)c1C1CC(Nc2nnnn12)c1cccc(Br)c1

InChI Key: InChIKey=VMLOOJNSJORYHE-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105257 (CHEMBL3597683) Show SMILES Fc1ccc(Cl)c(F)c1C1CC(Nc2nnnn12)c1cccc(Br)c1 Show InChI InChI=1S/C16H11BrClF2N5/c17-9-3-1-2-8(6-9)12-7-13(25-16(21-12)22-23-24-25)14-11(19)5-4-10(18)15(14)20/h1-6,12-13H,7H2,(H,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type His6-Gbeta1-fused HIF-2alpha PAS-B domain (240 to 350) (unknown origin) expressed in Escherichia coli by ITC analysis				J Med Chem 58: 5930-41 (2015) BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair