null
SMILES: Clc1cccc(c1)-c1ccc2n(Cc3ccccc3)c(=O)[nH]c2c1
InChI Key: InChIKey=JTJWERWUFWISDB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Progesterone receptor (Homo sapiens (Human)) | BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Binding affinity towards progesterone receptor was measured | Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line | Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cells | Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92 | |||||||||||
More data for this Ligand-Target Pair |