BDBM50105697 1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-2-[2-imino-3-(2-morpholin-4-yl-ethyl)-2,3-dihydro-benzoimidazol-1-yl]-ethanone::CHEMBL95632

SMILES: CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)Cn1c2ccccc2n(CCN2CCOCC2)c1=N

InChI Key: InChIKey=KMHNDSHZJUHLTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50105697 (1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-2-[2-imino-...) Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)Cn1c2ccccc2n(CCN2CCOCC2)c1=N Show InChI InChI=1S/C29H40N4O3/c1-28(2,3)21-17-20(18-22(26(21)35)29(4,5)6)25(34)19-33-24-10-8-7-9-23(24)32(27(33)30)12-11-31-13-15-36-16-14-31/h7-10,17-18,30,35H,11-16,19H2,1-6H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against potent thrombin receptor-1 (PAR-1) on human platelets				Bioorg Med Chem Lett 11: 2851-3 (2001) BindingDB Entry DOI: 10.7270/Q2NP23PC
					More data for this Ligand-Target Pair