BDBM50105756 4-[5-(4-Fluoro-phenyl)-3-isopropyl-3H-imidazol-4-yl]-pyrimidin-2-ylamine::CHEMBL316917

SMILES: CC(C)n1cnc(c1-c1ccnc(N)n1)-c1ccc(F)cc1

InChI Key: InChIKey=XVCSWAQWAKYULT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50105756 (4-[5-(4-Fluoro-phenyl)-3-isopropyl-3H-imidazol-4-y...) Show SMILES CC(C)n1cnc(c1-c1ccnc(N)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H16FN5/c1-10(2)22-9-20-14(11-3-5-12(17)6-4-11)15(22)13-7-8-19-16(18)21-13/h3-10H,1-2H3,(H2,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition against Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 11: 2867-70 (2001) BindingDB Entry DOI: 10.7270/Q28G8K1F
					More data for this Ligand-Target Pair