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SMILES: Nc1nccc(n1)-c1c(ncn1C1CCS(=O)(=O)CC1)-c1ccc(F)cc1

InChI Key: InChIKey=ACYSKLVNHYXHFU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105758   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50105758
PNG
(4-[3-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyran-4-y...)
Show SMILES Nc1nccc(n1)-c1c(ncn1C1CCS(=O)(=O)CC1)-c1ccc(F)cc1
Show InChI InChI=1S/C18H18FN5O2S/c19-13-3-1-12(2-4-13)16-17(15-5-8-21-18(20)23-15)24(11-22-16)14-6-9-27(25,26)10-7-14/h1-5,8,11,14H,6-7,9-10H2,(H2,20,21,23)
PDB
MMDB

NCI pathway
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KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 390n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition against Mitogen-activated protein kinase p38 alpha

Bioorg Med Chem Lett 11: 2867-70 (2001)


BindingDB Entry DOI: 10.7270/Q28G8K1F
More data for this
Ligand-Target Pair