BDBM50106186 4‐Bromobenzamide (0151-Am)::4-Bromo-benzamide::CHEMBL339059
SMILES: NC(=O)c1ccc(Br)cc1
InChI Key: InChIKey=ZRWNRAJCPNLYAK-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM50106186 (4‐Bromobenzamide (0151-Am) | 4-Bromo-benzami...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia Curated by ChEMBL | Assay Description The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibition | J Med Chem 44: 3786-94 (2001) BindingDB Entry DOI: 10.7270/Q2B857DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
8-Oxoguanine DNA glycosylase-1 (OGG1) (Homo sapiens (Human)) | BDBM50106186 (4‐Bromobenzamide (0151-Am) | 4-Bromo-benzami...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 µL of OGG1 (125 nM) was mixed with 1 µL of inhibitor. In a separate tube, 1 µL of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair |