BDBM50106196 (1H )-Quinazolin-2,4-dione::1H-Quinazoline-2,4-dione (Benzoylenurea)::CHEMBL421646::Quinazoline-2,4-diol

SMILES: O=c1[nH]c2ccccc2c(=O)[nH]1

InChI Key: InChIKey=SDQJTWBNWQABLE-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50106196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase (Homo sapiens (Human))	BDBM50106196 ((1H )-Quinazolin-2,4-dione | 1H-Quinazoline-2,4-di...) Show SMILES O=c1[nH]c2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-12 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50106196 ((1H )-Quinazolin-2,4-dione | 1H-Quinazoline-2,4-di...) Show SMILES O=c1[nH]c2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-9 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50106196 ((1H )-Quinazolin-2,4-dione | 1H-Quinazoline-2,4-di...) Show SMILES O=c1[nH]c2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-2 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50106196 ((1H )-Quinazolin-2,4-dione | 1H-Quinazoline-2,4-di...) Show SMILES O=c1[nH]c2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-1 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50106196 ((1H )-Quinazolin-2,4-dione | 1H-Quinazoline-2,4-di...) Show SMILES O=c1[nH]c2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Perugia Curated by ChEMBL					Assay Description The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibition				J Med Chem 44: 3786-94 (2001) BindingDB Entry DOI: 10.7270/Q2B857DN
					More data for this Ligand-Target Pair