BDBM50106211 CHEMBL3598104

SMILES: CCC(F)(F)C(=O)N1CCC(CC1)O[C@H]1CC[C@@H](CC1)Oc1cnc(cn1)S(C)(=O)=O

InChI Key: InChIKey=RRZKJFUOXRQZDN-SHTZXODSSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50106211 (CHEMBL3598104) Show SMILES CCC(F)(F)C(=O)N1CCC(CC1)O[C@H]1CC[C@@H](CC1)Oc1cnc(cn1)S(C)(=O)=O |r,wU:17.21,wD:14.14,(-.23,10.62,;-1.3,10.01,;-1.31,8.47,;-.24,9.08,;-.24,7.85,;-2.65,7.7,;-3.71,8.33,;-2.65,6.16,;-3.99,5.4,;-4,3.86,;-2.66,3.08,;-1.33,3.85,;-1.32,5.39,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;1.33,.77,;,1.54,;2.67,-1.54,;4,-.77,;4,.77,;5.33,1.55,;6.67,.78,;6.67,-.76,;5.34,-1.53,;8,1.56,;9.06,2.18,;9.07,.95,;7.99,2.79,)| Show InChI InChI=1S/C20H29F2N3O5S/c1-3-20(21,22)19(26)25-10-8-16(9-11-25)29-14-4-6-15(7-5-14)30-17-12-24-18(13-23-17)31(2,27)28/h12-16H,3-11H2,1-2H3/t14-,15-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR119 by HTRF cAMP assay				Bioorg Med Chem Lett 25: 3034-8 (2015) BindingDB Entry DOI: 10.7270/Q2SB47JS
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Rattus norvegicus)	BDBM50106211 (CHEMBL3598104) Show SMILES CCC(F)(F)C(=O)N1CCC(CC1)O[C@H]1CC[C@@H](CC1)Oc1cnc(cn1)S(C)(=O)=O |r,wU:17.21,wD:14.14,(-.23,10.62,;-1.3,10.01,;-1.31,8.47,;-.24,9.08,;-.24,7.85,;-2.65,7.7,;-3.71,8.33,;-2.65,6.16,;-3.99,5.4,;-4,3.86,;-2.66,3.08,;-1.33,3.85,;-1.32,5.39,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;1.33,.77,;,1.54,;2.67,-1.54,;4,-.77,;4,.77,;5.33,1.55,;6.67,.78,;6.67,-.76,;5.34,-1.53,;8,1.56,;9.06,2.18,;9.07,.95,;7.99,2.79,)| Show InChI InChI=1S/C20H29F2N3O5S/c1-3-20(21,22)19(26)25-10-8-16(9-11-25)29-14-4-6-15(7-5-14)30-17-12-24-18(13-23-17)31(2,27)28/h12-16H,3-11H2,1-2H3/t14-,15-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at rat GPR119 by HTRF cAMP assay				Bioorg Med Chem Lett 25: 3034-8 (2015) BindingDB Entry DOI: 10.7270/Q2SB47JS
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50106211 (CHEMBL3598104) Show SMILES CCC(F)(F)C(=O)N1CCC(CC1)O[C@H]1CC[C@@H](CC1)Oc1cnc(cn1)S(C)(=O)=O |r,wU:17.21,wD:14.14,(-.23,10.62,;-1.3,10.01,;-1.31,8.47,;-.24,9.08,;-.24,7.85,;-2.65,7.7,;-3.71,8.33,;-2.65,6.16,;-3.99,5.4,;-4,3.86,;-2.66,3.08,;-1.33,3.85,;-1.32,5.39,;-2.67,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;1.33,.77,;,1.54,;2.67,-1.54,;4,-.77,;4,.77,;5.33,1.55,;6.67,.78,;6.67,-.76,;5.34,-1.53,;8,1.56,;9.06,2.18,;9.07,.95,;7.99,2.79,)| Show InChI InChI=1S/C20H29F2N3O5S/c1-3-20(21,22)19(26)25-10-8-16(9-11-25)29-14-4-6-15(7-5-14)30-17-12-24-18(13-23-17)31(2,27)28/h12-16H,3-11H2,1-2H3/t14-,15-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR119 by serum shift assay				Bioorg Med Chem Lett 25: 3034-8 (2015) BindingDB Entry DOI: 10.7270/Q2SB47JS
					More data for this Ligand-Target Pair