BDBM50106258 CHEMBL127636::{2-[1-(3-Chloro-benzenesulfonyl)-5-methoxy-1H-indol-3-yl]-ethyl}-dimethyl-amine

SMILES: COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=HMVDWYPJGVKJPZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50106258 (CHEMBL127636 | {2-[1-(3-Chloro-benzenesulfonyl)-5-...) Show SMILES COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H21ClN2O3S/c1-21(2)10-9-14-13-22(19-8-7-16(25-3)12-18(14)19)26(23,24)17-6-4-5-15(20)11-17/h4-8,11-13H,9-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.				J Med Chem 44: 3881-95 (2001) BindingDB Entry DOI: 10.7270/Q2T72GRW
					More data for this Ligand-Target Pair